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THE EFFECTS OF SYNOVIAL FLUID DEFICIENCY ON THE TEMPOROMAMDIBULAR JOINT TISSUE OF RABBITS

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Abstract

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ÀúÀÚ´Â ¾Ç°üÀý¾×ÀÇ °áÇÌÀÌ ¾Ç°üÀý Á¶Á÷¿¡ ¹ÌÄ¡´Â ¿µÇâÀ» ¾Ë±â À§ÇÏ¿©, °¡Å並 Àü½Å¸¶Ãë
½ÃŲ ÈÄ ¾Ç°üÀý ºÎÀ§¸¦ Àý°³ÇÏ¿© »ó°üÀý°­À» ³ëÃâ½ÃŲ ´ÙÀ½, °üÀý°­À» »ý¸®½Ä¿°¼ö·Î ¼¼Ã´ÇÑ
ÈÄ rubber drain À» »ðÀÔÇÏ¿© °üÀý¾×ÀÇ Áö¼ÓÀû °áÇÌÀ» À¯µµÇÏ¿´´Ù. °¡Åä ÃÑ 15¸¶¸®¸¦ »ç¿ëÇÏ
¿© ´ëÁ¶±º°ú ½ÇÇ豺À¸·Î ³ª´©¾î, ¼úÈÄ 1, 2, 3, 4ÁÖ¿¡ 3¸¶¸®¾¿ Èñ»ý½ÃÄÑ hematoxylin &
eosinÀ¸·Î ¿°»öÇÑ ÈÄ, ±¤ÇÐÇö¹Ì°æÀ¸·Î °üÂûÇÏ¿© ´ÙÀ½°ú °°Àº °á°ú¸¦ ¾ò¾ú´Ù.
1. Á¤»ó±ºÀÇ È°¸·³»¸·ÀÇ Ãþ¼ö´Â 2¡­3ÃþÀ̾úÀ¸¸ç, ½ÇÇ豺 1ÁÖ¿¡¼­´Â ¹Ì¸¸¼º ¼¼Æ÷Áõ½Ä¿¡ ÀÇ
ÇÏ¿© 8¡­10ÃþÀ¸·Î µÇ¾úÀ¸³ª, Á¡Â÷ °¨¼ÒÇÏ¿© 4ÁÖ±º¿¡¼­´Â 4¡­5ÃþÀ¸·Î µÇ¾ú´Ù. ¼¼Æ÷°£ °æ°è´Â
ºÒºÐ¸íÇÏ¿´°í, ¼¼Æ÷¹è¿­Àº ºÒ±ÔÄ¢ÇÏ¿´À¸¸ç ¼¼Æ÷ÇÙÀº ³ó¿°¼ºÀ» º¸¿´´Ù.
2. ¿°Áõ, Ç÷°üº¯È­ ¹× ³»¸·ÇÏÁ¶Á÷ÀÇ ºÎÁ¾Àº ½ÇÇ豺 2ÁÖ¿¡¼­ °¡Àå ½ÉÇÏ¿´À¸¸ç, ½ÇÇè 4ÁÖ±î
Áö Áö¼ÓµÇ¾ú´Ù.
3. ³»¸·ÇÏÁ¶Á÷ÀÇ ¼¶À¯È­´Â ½ÇÇ豺 3ÁÖ¿¡¼­ ¹ß»ýÇÏ¿©, ½ÇÇè 4ÁÖ¿¡¼­´Â ´õ¿í Áõ°¡µÇ¾ú´Ù.
4. °üÀý°­ÀÇ ¼¶À¯È­¿¡ ÀÇÇÏ¿© ½ÇÇ豺 3ÁÖ¿¡¼­ °üÀý°­ÀÌ Á¼¾ÆÁø °ÍÀ» º¼ ¼ö ÀÖ¾úÀ¸¸ç, ½ÇÇè
4ÁÖ¿¡¼­´Â ´õ¿í Áõ°¡µÇ¾ú°í, ÇÏ°üÀý°­¿¡´Â À¯Âø ¼Ò°ßµµ ³ªÅ¸³µ´Ù.
5. °üÀý¿øÆÇÀº °æµµÀÇ Á¡¾×¼º º¯È­¿Í ÇÔ²² ±³¿ø¼¶À¯ÀÇ º¯¼ºÀÌ ½ÇÇè 2ÁÖ¿¡¼­ ¹ß»ýÇÏ¿©, ½Ç
Çè 4ÁÖ¿¡´Â º¯¼ºÀÌ Áõ°¡µÇ¾ú´Ù.
#ÃÊ·Ï#
The synovial membrane of the temporomandibular joint lines all the intraarticular
structures except the articular cartilage of the articular eminence, fossa, the mandicular
condyle and the articular disc. The synovial membrane consists of two layers. The first
layer is a lining cell layer facing the joint space and called synovial intima. The second
layer is called subintimal or subsynovial tissue. The synovial membrane fulfills several
important functions in maintaining normal joint physiology and joint function. Synovitis
occurs when the level of cellular debris and the concentration of chemical mediators of
inflammation produce levels that the synovial membrane is unable to ingest, absorb or
process. So degeneration of temporomandibular joint may be increased by dificiency of
synovial fluid. After general anesthesia by intramuscular infection of ketamin, exposure
of TMJ of rabbit was done by preauricular approach.
After exposure, rubber drain was inserted into the upper joint cavity, to prevent
accumulation of synovial fluid. Penicillin G was used to prevent secondary infection for
3 days. Fifteen Rabbits were used for experiment, and subdivided into 5 group (one
normal group and 4 experimental groups, each subdivided group consisted in 3 rabbits).
Experimental group were taken after period of 1, 2, 3, 4 weeks. After euthansia, on bloc
excision of TMJ was done to make biopsy specimen.
The results were as follows ;
1. Layers of synovial intima were increased in experimental group, 8¡­10 layers in
first week group and 4¡­5 layers in fourth week group as compared with 2¡­3 layers in
normal group. 2. Inflammation, vascular change and subintimal edema were highest in
second week group, but continued to fourth week group. 3. Subintimal fibrosis occured
in second week group, and increased to fourth week group. 4. Due to fibrosis of joint
cavity space occured in the third week group, and increased to fourth week group. 5.
Degeneration of articular disc occurred in second week group and increased to fourth
week group.

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